Publications
- Brown KE, Fohner AE, Woodahl EL. Beyond the Individual: Community-Centric Approaches to Increase Diversity in Biomedical Research. Clin Pharmacol Ther, 113:509-517, 2023.
- Brown KE, Etrouth S, Jayachandran P, et al. Diversity in Clinical Pharmacology: A Call to Action. Clin Pharmacol Ther, 113:483-485, 2023.
- Venkatakrishnan K, Brown KE, Giacomini KM, van der Graaf PH. Diversity, Equity, and Inclusion: Translating Clinical Pharmacology for All. Clin Pharmacol Ther, 113:457-461, 2023.
- Brown KE and Woodahl EL. Engaging diversity in research: Does your drug work in overlooked populations? In: Overcoming Obstacles in Drug Discovery and Development: Surmounting the Insurmountable. Ed: He K, Hollenberg PF, Wienkers LC. Elsevier, Amsterdam, Netherlands, in press
- Leitch TM, Killam SR, Brown KE, Katseanes KC, George KM, Schwanke, C, Loveland J, Elias AF, Haney K, Krebsbach K, Muzquiz LI, Trinidad SB, Woodahl EL. Ensuring Equity: Pharmacogenetic Implementation in Rural and Tribal Communities. Front Pharmacol, 13:953142, 2022.
- Fohner AE, Killam SR, Volk KG, Woodahl EL. Advancing Equity in the Promise of Pharmacogenomics. In: Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation. Ed: Devine B, Boyce RD, Wiisanen K. Elsevier, Amsterdam, Netherlands, 2022.
- Burke W, Beans JA, Benally M, Cho MK, Garrison NA, Hiratsuka V, Hopkins S, Spicer PG, Tsosie KS, Woodahl EL, Yracheta JM, Thummel K. Values and practices to strengthen genetic research partnerships with Indigenous communities. Prog Community Health Partnersh, in press.
- Beans JA, Trinidad SB, Blacksher E, Hiratsuka VY, Spicer P, Woodahl EL, Boyer BB, Lewis CM, Gaffney PM, Garrison NA, Burke W. Communicating precision medicine research: multidisciplinary teams and diverse communities. Public Health Genomics, in press.
- Blacksher, E, Trinidad SB, Woodbury RB, Hopkins SE, Woodahl EL, Boyer BB, Burke W, Hiratsuka, V. Tribal deliberations about precision medicine research: Addressing diversity and inequity in democratic deliberation design and evaluation. J Empire Res Hum Res Ethics, 17:304-316, 2022.
- Brown KE, Staples JW, Woodahl EL. Keeping pace with CYP2D6 haplotype discovery: Innovative methods to assign function. Pharmacogenomics, 23:255-262, 2022.
- Trinidad SB, Blacksher E, Woodbury RB, Hopkins SE, Burke W, Woodahl EL, Boyer BB, Hiratsuka, VY. Precision medicine research with American Indian and Alaska Native communities: Results of a deliberative engagement with Tribal leaders. Genet Med, 24:622-630, 2022.
- Sangkuhl K, Claudio-Campos K, Cavallari LH, Agúndez JAG, Whirl-Carrillo M, Duconge J, Del Tredici AL, Wadelius M, Botton MR, Woodahl EL, Stuart SA, Klein TE, Pratt VM, Daly AK, Gaedigk A. PharmVar GeneFocus: CYP2C9. Clin Pharmacol Ther, 110:662-676, 2021.
- Fohner AE, Dalton R, Skagen K, Jackson K, Claw KG, Hopkins SE, Robinson R, Khan BA, Prasad B, Schuetz EG, Nickerson DA, Thornton TA, Dillard DA, Boyer BB, Thummel KE, Woodahl EL. Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function. Clin Transl Sci, 14:1292-1302, 2021.
- Botton MR, Whirl-Carrillo M, Del Tredici AL, Sangkuhl K, Cavallari LH, Agúndez JAG, Duconge J, Lee MTM, Woodahl EL, Claudio-Campos K, Daly AK, Klein TE, Pratt VM, Scott SA, Gaedigk A. PharmVar GeneFocus: CYP2C19. Clin Pharmacol Ther, 109:352-366, 2021.
- McInnes G, Dalton R, Sangkuhl K, Whirl-Carrillo M, Lee S, Tsao PS, Gaedigk A, Altman RB, Woodahl EL. Transfer learning enables prediction of CYP2D6 haplotype function. PLoS Comput Biol, 16:e1008399, 2020.
- Staples JW, Stine JM, Mäki-Lohiluoma E, Steed E, George KM, Thompson CM, Woodahl EL. Food Dyes as P-glycoprotein Modulators. Food Chem Toxicol, 146:111785, 2020.
- Dalton R, Lee S, Claw KG, Prasad B, Phillips BR, Shen DD, Wong LH, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, Gaedigk A, Thummel KE, Woodahl EL. Interrogation of CYP2D6 structural variant alleles improves the correlation between CYP2D6 genotype and CYP2D6-mediated metabolic activity. Clin Transl Sci 13:147-156, 2020.
- Fohner AE, Volk KG, Woodahl EL. Democratizing Precision Medicine Through Community Engagement. Clin Pharmacol Ther 106:488-490, 2019.
- Lee SB, Wheeler MM, Patterson K, McGee S, Dalton R, Woodahl EL, Gaedigk A, Thummel KE, Nickerson DA. Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model. Genet Med 21:361-372, 2019.
- Khan BA, Robinson R, Fohner AE, Muzquiz LI, Schilling BD, Beans JA, Olnes MJ, Trawicki L, Frydenlund H, Laukes C, Beatty P, Phillips B, Nickerson D, Howlett K, Dillard DA, Thornton TA, Thummel KE, Woodahl EL. Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People. Clin Transl Sci 11:312-321, 2018.
- Henderson LM, Claw KG, Woodahl EL, Robinson RF, Boyer BB, Burke W, Thummel KE. P450 Pharmacogenetics in Indigenous North American Populations. J Pers Med 8, 9: 1-33, 2018.
- Morales CT, Muzquiz LI, Howlett K, Azure B, Bodnar B, Finley V, Incashola T, Mathias C, Laukes C, Beatty P, Burke W, Pershouse MA, Putnam EA, Trinidad SB, James R, Woodahl EL. Partnership with the Confederated Salish and Kootenai Tribes: Establishing an Advisory Committee for Pharmacogenetic Research. Prog Community Health Partnersh 10:173-83, 2016.
- Blunston MA, Yonovitz A, Woodahl EL, Smolensky MH. Gentamicin-Induced Ototoxicity and Nephrotoxicity Vary with Circadian Time of Treatment and Entail Separate Mechanisms. Chronobiol Int 32:1223-32, 2015.
- Lacher SE, Skagen K, Veit J, Dalton R, Woodahl EL. P-glycoprotein Transport of Neurotoxic Pesticides. J Pharmacol Exp Ther 355:99-107, 2015.
- Trahey M Li MJ, Kwon H, Woodahl EL, McClary WD, Atkins WM. Applications of Lipid Nanodiscs for the Study of Membrane Proteins by Surface Plasmon Resonance. Curr Protoc Protein Sci 81:29.13.1-29.13.16, 2015.
- Dorfman EH, Trinidad SB, Morales CT, Howlett K, Burke W, Woodahl EL. Pharmacogenomics in Diverse Practice Settings: Implementation Beyond Major Metropolitan Areas. Pharmacogenomics 16:227-37, 2015.
- Woodahl EL, Lesko LJ, Hopkins S, Robinson RF, Thummel KE, Burke W. Pharmacogenetic Research in Partnership with American Indian and Alaska Native Communities. Pharmacogenomics 15:1235-41, 2014.
- James R, Tsosie R, Sahota P, Parker M, Dillard D, Sylvester I, Lewis J, Klejka J, Muzquiz L, Olsen P, Whitener R, Burke W; Kiana Group*. Exploring pathways to trust: a tribal perspective on data sharing. Genet Med 16:820-6, 2014. *Woodahl EL (member of Kiana Group)
- Lacher SE, Gremaud JN, Skagen K, Steed E, Dalton R, Sugden KD, Cardozo-Pelaez F, Sherwin CMT, Woodahl EL. Absence of P-glycoprotein Transport in the Pharmacokinetics and Toxicity of the Herbicide Paraquat. J Pharmacol Exp Ther 348:336-45, 2014.
- Fohner A, Muzquiz LI, Austin MA, Gaedigk A, Gordon A, Thornton T, Rieder MJ, Pershouse MA, Putnam EA, Howlett K, Beatty P, Thummel KE, Woodahl EL. Pharmacogenetics in American Indian Populations: Analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes. Pharmacogenet Genomics 23:403-14, 2013.
- McCune JS, Woodahl EL, Furlong T, Storer B, Wang J, Heimfeld S, Deeg HJ, O'Donnell PV. A Pilot Pharmacologic Biomarker Study of Busulfan and Fludarabine in Hematopoietic Cell Transplant Recipients. Cancer Chemother Pharmacol 69:263-72, 2012.
- Boyer BB, Dillard D, Woodahl EL, Whitener R, Thummel KE, Burke W. Ethical Issues in Developing Pharmacogenetic Research Partnerships with Indigenous Communities. Clin Pharmacol Ther 89:343-5, 2011.
- Woodahl EL, Crouthamel MH, Bui T, Shen DD, Ho RJY. MDR1 (ABCB1) G1199A (SER400ASN) Polymorphism Alters Transepithelial Permeability and Sensitivity to Anticancer Agents. Cancer Chemother Pharmacol 64:183-188, 2009.
- Woodahl EL, Wang J, Heimfeld S, Sandmaier BM, McCune JS. Intracellular Disposition of Fludarabine Triphosphate in Human Natural Killer Cells. Cancer Chemother Pharmacol 63:959-964, 2009.
- Woodahl EL, Wang J, Heimfeld S, Sandmaier BM, O'Donnell PV, Phillips B, Risler L, Blough DK, McCune JS. A Novel Phenotypic Method To Determine Fludarabine Triphosphate Accumulation in T-Lymphocytes from Hematopoietic Cell Transplantation Patients. Cancer Chemother Pharmacol 63:391-401, 2009.
- Woodahl EL, Wang J, Heimfeld S, Ren AG, McCune JS. Imatinib Inhibition of Fludarabine Uptake in T-Lymphocytes. Cancer Chemother Pharmacol 62:735-739, 2008.
- Woodahl EL, Hingorani SR, Wang J, Guthrie KA, McDonald GB, Batchelder A, Li M, Schoch HG, McCune JS. Pharmacogenomic Associations in ABCB1 and CYP3A5 with Acute Kidney Injury and Chronic Kidney Disease after Myeloablative Hematopoietic Cell Transplantation. Pharmacogenomics J 8:248-255, 2008.
- Woodahl EL, Yang Z, Bui T, Shen DD, Ho RJY. MDR1 G1199A Polymorphism Alters Permeability of HIV Protease Inhibitors Across P-glycoprotein-Expressing Epithelial Cells. AIDS 14:1617-1625, 2005.
- Woodahl EL and Ho RJY. The Role of MDR1 Genetic Polymorphisms in Interindividual Variability in P-glycoprotein Expression and Function. Curr Drug Metab 5:11-19, 2004.
- Woodahl EL and Ho RJY. Augmentation of Cell-Mediated Immunity to Virus. In: Cellular Drug Delivery: Principle and Practice. Ed: D. Robert Lu and Svein Øie, Humana Press Inc., Totowa, NJ, 2004.
- Woodahl EL, Yang Z, Bui T, Shen DD, Ho RJY. Multidrug Resistance Gene G1199A Polymorphism Alters Efflux Transport Activity of P-glycoprotein. J Pharmacol Exp Ther 310:1199-1207, 2004.
- Yang Z, Woodahl EL, Wang XY, Bui T, Shen DD, Ho RJY. Semi-Quantitative RT-PCR Method to Estimate Full-Length mRNA Levels of the Multidrug Resistance Gene. Biotechniques 33:196-203, 2002.