BMED Publications

Recent Publications

Azaphilones from an Acid Mine Extremophile Strain of a Pleurostomophora sp. Stierle AA, Stierle DB, Girtsman T, Mou TC, Antczak C, et al. Journal of natural products. 2015 Dec 24; 78(12):2917-23. 

pH-Sensitive ionomeric particles obtained via chemical conjugation of silk with poly(amino acid)s. Serban MA, Kaplan DL. Biomacromolecules. 2010 Dec 13; 11(12):3406-12.

Novel di-aryl-substituted isoxazoles act as noncompetitive inhibitors of the system Xc(-) cystine/glutamate exchanger. Newell JL, Keyari CM, McDaniel SW, Diaz PJ, Natale NR, et al. Neurochemistry international. 2014 Dec 11; 73:132-8.

Absence of P-glycoprotein transport in the pharmacokinetics and toxicity of the herbicide paraquat. Lacher SE, Gremaud JN, Skagen K, Steed E, Dalton R, et al. The Journal of pharmacology and experimental therapeutics. 2014 Dec 2; 348(2):336-45.

Novel Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 Esslinger CS, Kavanaugh M, Lyda B, Natale NR. USA 8,895,607. 2014 November 25.

Prostaglandin I₂promotes the development of IL-17-producing γδ T cells that associate with the epithelium during allergic lung inflammation. Jaffar Z, Ferrini ME, Shaw PK, FitzGerald GA, Roberts K. Journal of immunology (Baltimore, Md. : 1950). 2011 Nov 15.

Prostaglandin I₂promotes the development of IL-17-producing γδ T cells that associate with the epithelium during allergic lung inflammation. Jaffar Z, Ferrini ME, Shaw PK, FitzGerald GA, Roberts K. Journal of immunology (Baltimore, Md. : 1950). 2011 Nov 15;187(10):5380-91.

Efficacy of interventions targeting household air pollution from residential wood stoves.; Ward TJ, Semmens EO, Weiler E, Harrar S, Noonan CW. Journal of exposure science & environmental epidemiology. 2015 Nov 11.

PEG modified liposomes containing CRX-601 adjuvant in combination with methylglycol chitosan enhance the murine sublingual immune response to influenza vaccination. Oberoi HS, Yorgensen YM, Morasse A, Evans JT, Burkhart DJ. Journal of controlled release : official journal of the Controlled Release Society. 2015 Nov 6; 223:64-74.

Alterations in DNA methylation and airway hyperreactivity in response to in utero exposure to environmental tobacco smoke. Lee JW, Jaffar Z, Pinkerton KE, Porter V, Postma B, et al. Inhalation toxicology. 2015 Nov 2 (13):724-30.

Silk-based monomeric compositions. Kaplan DL, Serban MA. Trustees of Tufts College, assignee. US 13/582903. 2012 October 31.

Berkeleyones and related meroterpenes from a deep water acid mine waste fungus that inhibit the production of interleukin 1-β from induced inflammasomes. Stierle DB, Stierle AA, Patacini B, McIntyre K, Girtsman T, et al. Journal of natural products. 2011 Oct 28; 74(10):2273-7.

Gentamicin-induced ototoxicity and nephrotoxicity vary with circadian time of treatment and entail separate mechanisms. Blunston MA, Yonovitz A, Woodahl EL, Smolensky MH. Chronobiology international. 2015 Oct 27; 32(9):1223-32.

Methylglycol chitosan and a synthetic TLR4 agonist enhance immune responses to influenza vaccine administered sublingually. Spinner JL, Oberoi HS, Yorgensen YM, Poirier DS, Burkhart DJ, et al. Vaccine. 2015 Oct 26; 33(43):5845-53.

Functionalization of silk material by avidin-biotin interaction. Kaplan DL, Wang X, Serban MA. Trustees of Tufts College, assignee. US US8293486. 2013 October 23.

Bioactive Secondary Metabolites Produced by the Fungal Endophytes of Conifers. Stierle AA, Stierle DB. Natural product communications. 2015 Oct 10; 10(10):1671-82.

Preparation and evaluation of natural scaffold materials for kidney regenerative applications. Serban MA, Knight TA, Payne RG. Methods in molecular biology (Clifton, N.J.). 2013; 1001:133-43.

Health impacts of anthropogenic biomass burning in the developed world. Sigsgaard T, Forsberg B, Annesi-Maesano I, Blomberg A, Bølling A, et al. The European respiratory journal. 2015 Sep 24; 46(6):1577-88.

Silk fibroin and polyethylene glycol-based biocompatible tissue adhesives. Serban MA, Panilaitis B, Kaplan DL. Journal of biomedical materials research. Part A. 2011 Sep 15; 98(4):567-75. 

Modular elastic patches: mechanical and biological effects. Serban MA, Kluge JA, Laha MM, Kaplan DL. Biomacromolecules. 2010 Sep 13; 11(9):2230-7. 

Natural Foxp3(+) regulatory T cells inhibit Th2 polarization but are biased toward suppression of Th17-driven lung inflammation. Girtsman T, Jaffar Z, Ferrini M, Shaw P, Roberts K. Journal of leukocyte biology. 2010 Sep 8.

Implantable medical devices. Serban MA, Burke SE, Daunch WA, Patel V, Jones BW, et al. Allergan Medical, assignee. US US2014/052264. 2014 August 22.

 

Silk medical devices. Serban MA. Allergan Medical, assignee. US US 13/973,818. 2013 August 22.

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, et al. Nature communications. 2015 Aug 20;6:8013.

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, et al. Nature communications. 2015 Aug 20; 6:8013. 

P-Glycoprotein Transport of Neurotoxic Pesticides. Lacher SE, Skagen K, Veit J, Dalton R, Woodahl EL. The Journal of pharmacology and experimental therapeutics. 2015 Aug 13; 355(1):99-107.

Medical device with anti-adhesive property. Serban MA, Burke SE, Daunch WA, Patel V, Jones B. Allergan Medical, assignee. US 14/458549. 2014 August 13.

Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection. Hughes TS, Wilson HD, de Vera IM, Kojetin DJ. PloS one. 2015 Aug 4; 10(8):e0134474.

Applications of Lipid Nanodiscs for the Study of Membrane Proteins by Surface Plasmon Resonance. Trahey M, Li MJ, Kwon H, Woodahl EL, McClary WD, et al. Current protocols in protein science / editorial board, John E. Coligan ... [et al.]. 2015 Trahey M, Li MJ, Kwon H, Woodahl EL, McClary WD, et al. Current protocols in protein science / editorial board, John E. Coligan ... [et al.]. 2015 Aug 3; 81:29.13.1-29.13.16. 81:29.13.1-29.13.16. 

The effect of bromine scanning around the phenyl group of 4-phenylquinolone derivatives. Steiger SA, Monacelli AJ, Li C, Hunting JL, Natale NR. Acta crystallographica. Section C, Structural chemistry. 2014 Jul 31; 70(Pt 8):790-5.

Anticancer compounds derived from fungal endophytes: their importance and future challenges. Kharwar RN, Mishra A, Gond SK, Stierle A, Stierle D. Natural product reports. 2011 Jul 28;1208-28.

Therapeutic formulations. Basu J, Payne R, Robbins NF, Knight OA, Jain D, et al. Tengion, assignee. US 13/883433. 2013 July 26.

S-nitrosoglutathione reductase inhibition regulates allergen-induced lung inflammation and airway hyperreactivity. Ferrini ME, Simons BJ, Bassett DJ, Bradley MO, Roberts K, et al. PloS one. 2013 Jul 25.

Crystal structure and absolute configuration of preaustinoid A1. Stierle A, Stierle D, Decato D. Acta crystallographica. Section E, Crystallographic communications. 2015 Jul 22; 71(Pt 8):o596-7.

Silk fibroin and polyethylene glycol-based biomaterials.  Kaplan DL, Serban MA. Trustees of Tufts College, assignee. US 13/820440. 2013 July 17.

Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain. Xu JJ, Diaz P, Astruc-Diaz F, Craig S, Munoz E, Naguib M. Anesth Analg. 2010 Jul;111(1):99-109. 

Bioactive secondary metabolites from acid mine waste extremophiles. Stierle AA, Stierle DB. Natural product communications. 2014 Jul 9; 9(7):1037-44.

Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-di-hydro-pyridine-3,5-di-carboxyl-ate. Steiger SA, Monacelli AJ, Li C, Hunting JL, Natale NR. Acta crystallographica. Section E, Structure reports online. 2014 Jun 18; 70(Pt 7):o791-2.

Pharmacogenetic research in partnership with American Indian and Alaska Native communities. Woodahl EL, Lesko LJ, Hopkins S, Robinson RF, Thummel KE, et al. Pharmacogenomics. 2014 Jun 15; 15(9):1235-41.

Pharmacological repression of PPARγ promotes osteogenesis. Marciano DP, Kuruvilla DS, Boregowda SV, Asteian A, Hughes TS, et al. Nature communications. 2015 Jun 12;6:7443.

Pharmacological repression of PPARγ promotes osteogenesis. Marciano DP, Kuruvilla DS, Boregowda SV, Asteian A, Hughes TS, et al. Nature communications. 2015 Jun 12; 6:7443.

Methods to monitor monocytes-mediated amyloid-beta uptake and phagocytosis in the context of adjuvanted immunotherapies. Hallé M, Tribout-Jover P, Lanteigne AM, Boulais J, St-Jean JR, et al. Journal of immunological methods. 2015 May 19; 424:64-79.

Exploring pathways to trust: a tribal perspective on data sharing. James R, Tsosie R, Sahota P, Parker M, Dillard D, et al. Genetics in medicine : official journal of the American College of Medical Genetics. 2014 May 15; 16(11):820-6.

Multiple pathway asbestos exposure assessment for a Superfund community.Noonan CW, Conway K, Landguth EL, McNew T, Linker L, et al. Journal of exposure science & environmental epidemiology. 2015 Apr 23; 25(1):18-25.

Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia cell lines. Stierle AA, Stierle DB, Girtsman T. Journal of natural products. 2012 Mar 23; 75(3):344-50. 

Crosslinked silk-hyaluronic acid compositions. Pavlovic E, Serban MA, Yu X, Manesis NJ. Allergan Medical, assignee. US 13/868010. 2013 April 22.

AIMing towards improved antitumor efficacy. Weaver MJ, Kearns AK, Stump S, Li C, Gajewski MP, Rider KC, Backos DS, Reigan PR, Beall HD, Natale NR. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1765-70. doi: 10.1016/j.bmcl.2015.02.063. 

Indoor particulate matter in rural, wood stove heated homes. Semmens EO, Noonan CW, Allen RW, Weiler EC, Ward TJ. Environmental research. 2015 Apr 15; 138:93-100.

Evaluating the effect of ambient particulate pollution on DNA methylation in Alaskan sled dogs: potential applications for a sentinel model of human health. Montrose L, Noonan CW, Cho YH, Lee J, Harley J, et al. The Science of the total environment. 2015 Apr 15; 512-513:489-94.

AIMing towards improved antitumor efficacy. Weaver MJ, Kearns AK, Stump S, Li C, Gajewski MP, et al. Bioorganic & medicinal chemistry letters. 2015 Apr 15; 25(8):1765-70.

Structural requirements for TLR7-selective signaling by 9-(4-piperidinylalkyl)-8-oxoadenine derivatives. Bazin HG, Li Y, Khalaf JK, Mwakwari S, Livesay MT, et al. Bioorganic & medicinal chemistry letters. 2015 Mar 15; 25(6):1318-23.

Cross-linked gelatin microspheres with continuously tunable degradation profiles for renal tissue regeneration. Serban MA, Knight T, Payne RG, Basu J, Rivera EA, et al. Biotechnology and applied biochemistry. 2014 Mar-Apr; 61(2):75-81.

Spinal gene expression profiling and pathways analysis of a CB2 agonist (MDA7)-targeted prevention of paclitaxel-induced neuropathy. Xu JJ, Diaz P, Bie B, Astruc-Diaz F, Wu J, Yang H, Brown DL, Naguib M. Neuroscience. 2014 Feb 28;260:185-94.

Caspase-1 and -3 inhibiting drimane sesquiterpenoids from the extremophilic fungus Penicillium solitum. Stierle DB, Stierle AA, Girtsman T, McIntyre K, Nichols J. Journal of natural products. 2012 Feb 24; 75(2):262-6. 

Ethyl 3-(9-chloro-10-oxo-9,10-di-hydro-anthracen-9-yl)-5-methyl-isoxazole-4-carboxyl-ate. Duncan NS, Beall HD, Kearns AK, Li C, Natale NR. Acta crystallographica. Section E, Structure reports online. 2014 Feb 19; 70(Pt 3):o315-6.

In vivo efficacy of enabling formulations based on hydroxypropyl-β-cyclodextrins, micellar preparation, and liposomes for the lipophilic cannabinoid CB2 agonist, MDA7. Astruc-Diaz F, McDaniel SW, Xu JJ, Parola S, Brown DL, Naguib M, Diaz P. J Pharm Sci. 2013 Feb;102(2):352-64.

Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains. Khalaf JK, Bowen WS, Bazin HG, Ryter KT, Livesay MT, et al. Bioorganic & medicinal chemistry letters. 2015 Feb 1; 25(3):547-53.

Estimating the number of vulnerable people in the United States exposed to residential wood smoke.; Noonan CW, Ward TJ, Semmens EO. Environmental health perspectives. 2015 Feb 1; 123(2):A30.

Dust Allergens within Rural Northern Rocky Mountain Residences. Weiler E, Semmens E, Noonan C, Cady C, Ward T. Jacobs journal of allergy and immunology. 2015 Jan 23; 1(2):1-6.

Redetermination and absolute configuration of berkeleydione. Stierle A, Stierle D, Decato D. Acta crystallographica. Section E, Crystallographic communications. 2015 Mar 21; 71(Pt 4):o248.

Pharmacogenomics in diverse practice settings: implementation beyond major metropolitan areas. Dorfman EH, Brown Trinidad S, Morales CT, Howlett K, Burke W, et al. Pharmacogenomics. 2015 Dec. 3; 16(3):227-37.

Bioactive Natural Products. Stierle A, Stierle D. Rahman A, editor. Amsterdam: Elsevier Science Publishers; 2013. Bioprospecting in the Berkeley Pit: the Use of Signal Transduction Enzyme Inhibition Assays to Isolate Bioactive Secondary Metabolites from the Extremophilic Fungi of an Acid Mine Waste Lake; p.1-47.