Pharmacy Program
Undergraduate Research
Cyberbear
Moodle
Toxicology
Toxicology lab groups in BMED are investigating the molecular, cellular, and physiological effects of environmental agents and their capacity to trigger or exacerbate human diseases involving the respiratory, immune, gastrointestinal and nervous systems.
Understanding the mechanisms and consequences of environmental agents on human health has been a longstanding area of interest that is both shared by a large number BMED faculty and reflects the traditional ties between toxicology and pharmacology often found in Schools of Pharmacy. The University's Center for Environmental Health Sciences (CEHS), which is housed in BMED, has been key to the growth of research in the field environmental toxicology through its active support of collaborative projects, instrumentation cores, and graduate training. BMED faculty are investigating the physiological effects of a wide range of agents (e.g., nanomaterials, industrial chemicals, pesticides, airborne particulate matter), with a focus on their ability to trigger or exacerbate disease processes in the respiratory, immune, gastrointestinal and nervous systems. The potential mechanistic contributions of inflammation to these apparently disparate pathologies also serve as exciting points of interaction between numerous BMED lab groups. Ongoing research in environmental health is also enhanced by work in exposure assessment, genetics, epigenetics, and epidemiology along with population-based research. A list of BMED faculty interests in Toxicology can be found below.
Students working in the CEHS labs have pursued their graduate degrees in:
Howard D. Beall
Dean, Skaggs School of Pharmacy
Mechanisms of toxicity of novel, targeted anticancer agents.
Celine Beamer
Research Associate Professor
Lilian Calderón-Garcidueñas
Professor
Fernando Cardozo-Pelaez
Professor
Yoon Hee Cho
Associate Professor
Development of Epigenetic biomarkers for inhaled air pollutants and lung disease
Douglas Coffin
Professor of Molecular Genetics
Developmental toxicology: Stem cell differentiation, molecular and genetic basis of mammalian growth and development.
Andrij Holian
Professor, Director of Center for Environmental Health Science
Zeina Jaffar
Research Assistant Professor
Christopher T. Migliaccio
Research Associate Professor
Curtis Noonan
Professor and Director, Center for Population Health
Mark Pershouse
Associate Professor
Liz Putnam
Chair, Professor
Understanding the control of protein production related to lung fibrosis, using asbestos-caused fibrosis as a model system.
Kevan Roberts
Associate Professor
David Shepherd
Professor
The Shepherd laboratory is interested in understanding how environmental pollutants (Dioxins, PCBs) affect dendritic cells, the professional antigen presenting cells in the body.